Showing posts with label influenza. Show all posts
Showing posts with label influenza. Show all posts

Wednesday, November 18, 2009

Influenza Series, Part IV: The tricky part for me--making sense of risk

I started writing this series on influenza because I felt compelled to write about my fears--both the reasonable aspect of them, and the more extreme. My goal for each of these posts is not only to show some of the research I've done, but also to let you into the workings of my mind on this. The photos of clockwork gears that you see throughout are my attempt to represent that process.


I said at the outset of this post series that my worries about H1N1/09 are only amplified because of my own tendencies to crave control and fear illness. A fear of illness, is, of course, an ultimate expression of the need for control over chaos. I recognize all of this about myself. I'm constantly grappling with my judgement about risk, questioning whether my worries are based in logic or not.

In most areas of life, I know that from time to time I downplay real risks, as a way of minimizing my worries, and I know that, conversely, sometimes I overcorrect by being too cautious. Fortunately, what was once more of a constant obsession now only surfaces from time to time; when these worries do surface, they don't stay long.

However, in the spring of 2009, the advent of H1N1 brought my anxieties about health into clear, focused energy once more.

I remember I was in our kitchen, cleaning up the dishes from a Sunday morning pancake breakfast when I saw the first footage coming from Mexico City. The headline said something about influenza, and the reporter was wearing a white face mask. My own transformation was extraordinary. A fear that I had set aside years ago came roaring back like a wind in my head, and I abandoned the dishes to follow the story.

As the numbers of infected and seriously ill people in Mexico were reported, I grew more concerned. The new classification as "swine flu" made me think immediately of 1918. I told a few people about my worries for what may be coming down the pike, feeling like a Cassandra.

Meanwhile the world spun neatly on its axis. Spring blossomed in our yard as quietly and gently as every other year. The sky, to my relief, did not crash down. H1N1 continued in its elegant way to infect people all over the world, enough people, in fact, that the WHO declared it pandemic by early June.

For the most part, I kept sane about it. No, I didn't stop traveling, nor going to public places like theaters. But I did have that nagging feeling that this fall may bring a surprise with it.

Now we are well into the fall, and I feel the pull between the reasonable and the extreme each time I consider the "what to do" about the H1N1 situation.


What I'm doing:
I'm attempting to get the vaccine for us. Ada has had one dose, and needs a followup that may come by January. Esme and I have had no luck in locating one, though I check clinics a few times a week. My husband should get one at work, but--like everyone else's--his vaccinations have been delayed.

I'm also practically swimming in alcohol-based hand cleaners. The girls are pretty well trained on washing up after every trip outside, and before meals, and after visits, and on getting in the car...and so on. Ada tries to be conscientious about that stuff at school, as much as she can. And I have her change her clothes when she comes home from school.

When a whopping 20% of her school was out, we kept Ada home for over a week. After 10 days, it was my hope her first vaccine had at least kick started an immune response against H1N1. A leap of faith for me, but...

I beg off shaking hands, saying "Oh, I've got a cold." Inoffensive, I hope--effective? Who knows? But it make me feel like I'm at least doing something...

What I want to do (but don't):
If I think about it too much, I sort of want to hide in our house. I get nervous about going to a big public gathering, especially one where there are lots of other little kids who sneeze, and wipe, and do all that gross stuff kids do (hey, I know--my kids do it, too.) I want to huddle down in our own little nest and just wait it all out. I want to beg or bribe or get that vaccine right now, and cross my fingers and cast some special spell to keep the flu away from us.



You might have noticed that many sensible and rational people, given the same facts, have a less alarmist reaction about getting this year's flu, or getting sick in general. They trust that whatever happens won't be so bad, that either it's no big deal to start with, or, if it does get to be a problem, that someone will take care of it.

Both of these sensible reactions are based on trust, and as I examine my own fears, I realize I don't feel it. At least not in this capacity. My own concern about the influenza outbreak this year is based on fact, yes--but it is amplified 100 times by my own insecurities.

As I've brooded, I've also tried to see my own process of worrying in an objective way. What is setting me off, I've wondered? I've wondered this especially as I find myself watching a newscast and replying back to the television, retorting something a reporter said about influenza. Why am I acting like this? This is not where I want my energy to go--into stridently arguing with a reporter on tv. Or reading every little thing I can about H1N1. When I step back far enough from myself, I can see that what Kirie is doing is called obsessing.


It's hard to admit that. It's hard to say that what I perceive as a real threat might not be as real to someone else. It makes the ground under me feel shaky. But the fact is there: my obsessions might be based on fact to start with, but they spiral way out of reach of normal at some point. And they tend to be related to my own need to control my environment, to create an illusion of impenetrable safety. On so many levels, I crave predictability, because it solidifies that illusion, like a playback loop whispering: all is well; you are safe. all is well; you are safe.


I've said that this year's H1N1 influenza scenario hits all my panic buttons. Essentially, for me it created two perfect storms. One of those storms is, certainly, the reality that this is a pandemic. The other storm is clearly in my mind--the storm of unpredictability and distrust.

The first issue for me is the unpredictability. The virus is unpredictable, and easily spread, even by people who seem well (because it is contagious even a day before symptoms appear). What appears to be one thing: "just flu" or "don't worry, I don't have it!" might be something else entirely. Of course, the flipsides to these (the ones that slip my mind too often) are a) most people who get sick with flu WILL NOT find themselves at death's door, and b)most people who are walking around town are not in a contagious state of influenza.

The second issue for me is the trust. Basically, I don't trust people in general to take this flu seriously. I really don't trust people to wash their hands, to cough in their sleeves. I don't trust that there will be adequate vaccinations for people who want them *before* the virus peaks. I don't really trust that a cold is just a cold at this point. If I hear someone is coughing, I'm assuming it's flu. I don't trust the media to give a clear portrayal of what flu is, or isn't. I don't trust the government to really stay on top of tracking the changes of the virus, to put funding toward a new method of making the vaccine. I don't trust people to believe me. (Ah, the irony!)

I don't trust, I don't trust. I hear these all strung along in my head as I write this and I feel another feeling echoing it: I feel lonely. That Cassandra-like sensation of being disbelieved is, at its heart, isolating. And overwhelming. Feeling isolated and overwhelmed are cues for me that my worries are not completely related to the influenza pandemic alone. Really, my worries are rooted in my past.


A little headshrinking: My childhood was relatively chaotic--my parents, though they loved me, were somewhat absentee. The day-to-day of my life was far from predictable, people's emotions were volatile--my own, my brother's, my parents'. My own physical environment felt out of my control, and very different from that of my peers. I often felt different and alone, and misunderstood by most people. I could not, if pressed, have imagined what my future would look like. I didn't really trust that I would have a real adulthood--because I couldn't imagine what that could be.


Of course, my adulthood did come to be. Sometime in my early 20s I discovered that I could try to shape my own existence a little. And in my grown-up life, I have predictability in abundance. Calm rules the day--literally, it leads the list of our family rules, which we have written out. Sure, there is the messiness of life with little kids, but it is joyful, and welcomed. Trust is the keystone between my husband and me, between my kids and me. I often catch myself saying to them, "You're doing great. You can do that. I trust you." And I do trust them. I have, as an adult, become faithful in a religious sense, and I trust God, too.



So--here is the contradiction, right: With all this goodness, and all this solid trust and predictability in my life, why worry? Why indeed? Because as much good and beauty as I see, I also get glimpses into the underbelly of life, too, and it unsettles me, deeply. There is room for both, I know. A need for both, in fact. I am practicing holding both the beautiful and the dreadful in my mind at once, and letting it be.

It was not my hope in writing this series to spin up fears, but rather to show how the genesis of my own worries about influenza. I also hoped that writing through my own thought process would help bring some clarity to me about why I have become obsessed. If you have gotten this far into my posts, you must see that, as a threat, influenza sits neatly someplace between something very scary and something to be brushed off as inconsequential. When you consider it, it's best to recognize both extremes as unreasonable, and try, as I am, to find some middle way.

Yes, H1N1 is frightening because it does have a potential to become a terrible flu--one that resembles 1918. Actually, that potential is in every influenza. Given those facts, any objective person would admit that flu shouldn't be taken lightly.

But of course, the potential is there for this to NOT become a deadly flu. And the numbers indicate--in fact, they indicated this in 1918 as well--that the vast majority of people who get influenza recover. Given those facts, any objective person would admit that hiding from the world doesn't actually mitigate the risk--the minimal risk.

The scary potential and the benign potential exist simultaneously, all the time, in all actions. Just writing about that uncertainty makes me catch my breath. I refocus, I breathe, I vow to accept that calmly. I have to push myself to remember these things, but I do. I do push past them and go out into the world, send Ada back to school, take Esme to swimming class, make my art, have playdates, Halloween parties, and see my friends and neighbors. To meet me, you would never guess at the contradictions wrestling each other in my mind, but they are there. And someday, I hope, to accept them without anxiety.



If you are interested in catching up with the rest of the series:

Tuesday, November 17, 2009

Part II on Influenza: a little primer to add to the barrage of information you've already gotten

Part II: Yet another primer on influenza

I know everyone is inundated with information about influenza these days. Still, a little about the basics makes sense in the context of my post, so here goes.

I've seen quite a few gaps in the explanation offered on the evening news, and I'm going to make an effort to fill some of those in. In the process, I hope to perhaps debunk a few of the myths that are circulating about what flu is and what it isn't. Bear with me, or skip ahead to part three, if you like. You may, with good reason, question my medical background and authority to write these definitions. No, I am not a doctor. But I am a great researcher, and what I have compiled here is based on that:

What influenza is:
A super-simple way to think of influenza is as a virus with an outer "shell." The shell is studded with two distinct glycoproteins, one which is sort of long and spiky, and one which is sort of squat and mushroom-shaped. Long and spiky is called hemagglutinin, or "H" for short. Shorty mushroom-shape is an enzyme (also a protein) called neuraminidase, or "N."
When a specific influenza is categorized, it is typed according to the proteins present on its shell. As of this writing, there are at least 16 variations of the "H" protein, and nine of the "N" enzyme. When you see "H1N1," you are seeing a name that refers to the types of surface structures on that specific strain of influenza.

Influenza is also categorized into types A, B, and C. These classifications, which dates back to the 1930s, offer a basic means of determining a variety of influenza, but they are quite general. The H1N1 circulating in 2009 is Influenza A.


When a type of flu is called "novel," as this year's H1N1 happens to be, it refers to a "new" strain of flu, essentially a combination of genetic material that hasn't been circulated before in a human population. The bits of genetic code in the novel flu aren't immediately recognized by most human immune systems. And all of this translates to more people becoming infected. People who study pandemics are especially interested in novel influenza.

How it is transmitted:
You know the basics about this: Tiny airborne particles from those already infected will expose you to the virus. You get these from breathing them in (from someone's cough or sneeze--ick!), or from touching a surface on which these little guys have been camping out. (By the way, they can wait patiently for a host for anything from a minute up to 48 hours, depending on the surface and the environment.) Once it gets into you (through your mucus membranes like eyes, mouth, nose), it basically turns you into a flu factory. The mechanism of how flu infects its hosts and replicates itself (humans and animals) is fascinating and frighteningly efficient. For a great example of a video that depicts it, check out this piece by Harvard's Medical school.

How it changes:
Influenza is a constant invader to humans because it's highly adaptive. First, the proteins on the surface change pretty frequently. Each change makes a slightly new virus, one that is newly unrecognizable to the human immune system. This is why the seasonal flu from last year is always different from the seasonal flu the year before, and so on. In an attempt to help create a wide range of antibodies for those vaccinated, each year's vaccine actually includes bits from several strains circulating the year before.
Influenza has yet another trick: when it replicates its RNA, the virus can exchange bits of genetic material with other influenza variants, even variants that infect primarily animals. This is why some strains of influenza have genetic material from avian or swine flu, or both. This year's version of H1N1 actually has all three.

What actually happens when a person gets infected with seasonal flu:
You know how this one goes, too. The symptoms of flu are generally related to the human immune system trying to expel the virus. Generally, after a 1-4 day incubation period, influenza has an extremely quick onset, that hits a person like a ton of bricks. Common symptoms are the headache, body aches, fever, chills, shaking, cough, sore throat, and weakness. If it's flu, you are flat-out sick in bed for at least 2 or 3 days, and more likely 5-7. Basically, it sucks. It's not uncommon for a cough to hang around after flu for up to 5 weeks, and post viral weakness can linger, too, for several weeks, especially in adults.


And for novel H1N1? What happens?
Well, keep in mind first that H1N1 is an influenza. The symptoms are similar. But because it is an influenza, it also has a range of symptoms and severity. I think it's worth noting that the Centers for Disease Control (CDC) has stated that a fever is not always present with this flu. The cough seems to be universal, as do the aches, fatigue, and sore throat. The incubation time is similar to a seasonal flu (1-4 days), and the recovery time is similar as well, but a person is contagious for at least one day after the symptoms disappear and--more problematic--a full day before the symptoms begin. Additionally, there is some speculation that the virus continues to be contagious several days after symptoms have abated, especially in children. The symptoms that can linger for weeks include a generalized weakness and a cough.


That is the very basic outline of what flu is. But my concern about influenza, and this particular strain, has more to do with what flu is not, than what it is. And that is the subject of Part III.

Monday, November 16, 2009

In-flu-enza: A post in several parts

A multi-part post in which I alternately stand on my soapbox and step down to muse a bit.

There was a little bird
Her name was Enza.

They opened up the window,
and in-flew-Enza.
--American jump-roping song popular in 1918-1919
PART I: Flu on my mind.

I've been debating for months whether to add my voice to the cacophonous bluster about flu that fills our media these days. I'm writing about it here because the whole pandemic influenza thing is not a new worry for me. I've been wary of it for many years, probably because it hits all my sorespots of worry and illness and control. I'll get more into that in the third part of this post series. For now, hang on for a bit while I hop up onto my lecture/soapbox and explain a few of my thoughts on it.

If you know me, you might well know that I have been, at times in my life, a fantastic worrier. But I'm also pretty damn willful, and I've been willing myself to let go of that worrying tendency. Over the past five years, I'd say it's actually starting to work.

Sometime in my anxiety-ridden twenties, I discovered completely by accident that I loved reading about history. And it brought an added benefit: visiting and studying the past was soothing, comforting. I am nostalgic at heart, and a sucker for a story--it's amazing it took me until my twenties to cultivate an interest in history. As I read more, I found myself not only drawn into the stories, but also calmed by the greater fact of history: the fact that life goes on.

Of course, looking to the past presents other problems. History is unconcerned with neat endings or safe outcomes. The past is, in its essence, a place peopled with figures who, right or wrong, with dignity or with disgrace, lived--and died. To embrace history is to make the admission that we, too, recede into the past; our lives will become simply remnants of stories, bits of ephemera that fade away.

Did I say earlier that I had willed myself away from worrying? That history soothes? Because that last paragraph is nothing if not melancholy. But as I consider history, I find a strange comfort in the juxtaposition it presents. Thinking about the past offers that rare chance to hold in the mind, simultaneously, the ideas of both mortality and hope.

The events of the 1918 influenza pandemic distilled these feelings for me, when I stumbled onto it. As I learned more about it, I had the feeling of discovery, as though I had unearthed some weird secret of the recent past. Of course, it's getting its fair share of play right now, but for decades, it was a largely forgotten story.

My interest in what happened in 1918 fostered a curiosity about influenza in general. And what I hope to do with this next posts is to share some of my thoughts and attempt to make some sense out of pandemic flu since I started thinking about it years ago.


Pandemics are nothing new. And--this part is important--pandemic does not necessarily mean deadly. Pandemic just means a disease significantly "spread worldwide." Simply because a virus has a high infection doesn't always necessarily mean that it's deadly for many people.
But influenza is a tricky virus, and it *can* be deadly. It's that unknown element that makes it frightening.
The past 900 years of European history is peppered with accounts of entire countries or continents being besieged with deadly respiratory disease. We would certainly consider these pandemics today. Many of these aren't well documented, but the descriptions that do exist bear a striking resemblance to what we know as novel influenza. Of course, the most well-documented pandemic in history is the one of 1918, which killed upwards of 50 million people worldwide. As a comparison point, consider this: 675,000 Americans died as a result of the 1918 influenza, more than twice the number of Americans who died fighting during World War I.

When I first encountered them, these figures stunned me. I mean, come on. Flu. Everyone gets flu once in a while, right? A sore throat, a fever, a few days of rest---and it's gone. Flu is no big deal, right? I was incredulous that the flu actually killed so many otherwise young and healthy people. My initial, childish reaction to these accounts came from fear and ignorance: I scoffed at the limits of medicine at the time. What a long way we've come since then, I reassured myself. Nothing like that could happen today.

Still, my curiosity had been piqued, and I read anything I could about 1918. And then anything I could about influenza in general.

The picture that started to form in my mind was less ill-informed, and more frightening. The pandemic of 1918 was a perfect storm of circumstance, and it was not unlike what is happening now with the 2009 H1N1.

I want to be clear: I'm not implying that history is repeating itself. The H1N1 virus of 2009, while similar in makeup to the virus of 1918 , is not the same virus, and the scenario is obviously different. I do not believe that the strain of influenza (Novel H1N1/2009) circulating at this point in time will kill 6% of our population. I do not believe we are seeing the beginnings of story to rival The Stand, or the bible (how strange to see those in a sentence together). Still, some things happening now with the current strain of H1N1 give me pause. And my alarm bell, though admittedly prone to go off, has started ringing.


And to skip to the reason on why I, in particular, am concerned: